Journal
MUSCLE & NERVE
Volume 24, Issue 4, Pages 512-516Publisher
WILEY
DOI: 10.1002/mus.1034
Keywords
depression; myasthenia gravis; quality of life
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The cardinal symptom of myasthenia gravis (MG) is weakness of voluntary muscles, a feature that may restrict full participation in life activities. In turn, such limitations may negatively affect quality of life (QOL) and well-being among individuals with the disease. In the present study, we administered a measure of QOL to 27 patients with generalized MG. Results revealed that functional status was negatively impacted in the domains of physical functioning, energy, and general health. However, a clinically meaningful difference was evident only on perceived ability to accomplish physical tasks. The results suggest that although MG requires accommodations in physical activities, general QOL and weft-being does not differ markedly from the general population. (C) 2001 John Wiley & Sons, Inc.
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