Journal
LEUKEMIA & LYMPHOMA
Volume 41, Issue 3-4, Pages 425-+Publisher
HARWOOD ACAD PUBL GMBH
DOI: 10.3109/10428190109057999
Keywords
chronic myelogenous leukemia; Kaposi's sarcoma; human herpesvirus-8; multiple neoplasms vinblastine
Categories
Ask authors/readers for more resources
We report here a 75-year-old man from South France who developed Kaposi`s Sarcoma (KS) 5 months after diagnosis of Philadelphia-chromosome positive chronic myelogenous leukemia (CML). He was found positive for HHV-8 by PCR, negative for both HIV 1 and HIV 2 by serology, and had a normal CD4/CD8 ratio. Favourable evolution of both CML and KS has been obtained with vinblastine and interferon alpha treatment, The patient is currently alive in complete remission of SK and major cytogenetic remission of CML with a 48 month follow-up. Since no immune deficiency could be documented in the patient, this rare observation suggests that CML may have triggered the onset of SK through cytokine release.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available