Monoindole alkaloids from a marine sponge Mycale fibrexilis

In this study, eleven monoindol alkaloids (1-11) were obtained from a marine sponge Mycale fibrexilis (order: Poecilosclerida, family: Mycalidae), of which compound 1 is new. Herein, we first report the chemical investigation on M. fibrexilis. The emergence of monoindole alkaloids is less common in the family Mycalidae, which implies that they might be specific chemical constituents for this species. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.