4.8 Article

Defibrillation via the elimination of spiral turbulence in a model for ventricular fibrillation

Journal

PHYSICAL REVIEW LETTERS
Volume 86, Issue 16, Pages 3678-3681

Publisher

AMERICAN PHYSICAL SOC
DOI: 10.1103/PhysRevLett.86.3678

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Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart make it incapable of any concerted pumping action. Methods of controlling ventricular fibrillation include electrical defibrillation as well as injected medication. Electrical defibrillation, though widely used, involves subjecting the whole heart to massive, and often counterproductive, electrical shocks. We propose a defibrillation method that uses a very low-amplitude shock (of order mV) applied for a brief duration (of order 100 ms) and over a coarse mesh of lines on our model ventricle.

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