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Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

Journal

TRENDS IN PLANT SCIENCE
Volume 6, Issue 5, Pages 219-226

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/S1360-1385(01)01922-7

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Funding

  1. NIGMS NIH HHS [R01 GM063879] Funding Source: Medline

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The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns.

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