Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 40, Issue -, Pages 821-825Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST20120055
Keywords
cisplatin; microRNA (miRNA); protein expression; tumour
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Funding
- Yorkshire Cancer Research [R/124217-11-1]
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Resistance to the cytotoxic effects of cisplatin can be mediated through changes in a wide variety of cellular processes and signalling pathways. The discovery of microRNAs as regulators of protein expression through the targeting of mRNA has led to a number of studies on the effect of cisplatin treatment on microRNA expression, and the ability of microRNAs to modulate cisplatin resistance.
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