Journal
NUTRITION
Volume 17, Issue 5, Pages 409-413Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0899-9007(01)00518-4
Keywords
insulin; tumor necrosis factor; inflammation; macrophage migration inhibitory factor; diabetes mellitus
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I suggest that insulin suppresses the secretion and antagonizes the harmful effects of tumor necrosis factor-alpha, macrophage migration-inhibitory factor, and superoxide anion. Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-a and macrophage migration-inhibitory factor have important roles.
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