Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 38, Issue -, Pages 104-109Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0380104
Keywords
budding yeast; checkpoint; DNA damage; proliferating-cell nuclear antigen (PCNA); replication; ubiquitin-processing protease (UBP)
Categories
Ask authors/readers for more resources
Eukaryotes ubiquitylate the replication factor PCNA (proliferating-cell nuclear antigen) so that it tolerates DNA damage. Although, in the last few years, the understanding of the evolutionarily conserved mechanism of ubiquitylation of PCNA, and its crucial role in DNA damage tolerance, has progressed impressively, little is known about the deubiquitylation of this sliding clamp in most organisms. in the present review, we will discuss potential molecular mechanisms regulating PCNA deubiquitylation in yeast.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available