Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 38, Issue -, Pages 54-59Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0380054
Keywords
adrenal cortex; small ubiquitin-related modifier (SUMO); steroidogenesis; steroid receptor; SUMOylation; ubiquitylation
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Steroid hormones control many aspects of animal physiology and behaviour. They are highly regulated, among other mechanisms, by post-translational modifications of the transcription factors involved in their synthesis and response. In the present review, we will focus on the influence of SUMO (small ubiquitin-related modifier) and ubiquitin modifications on the function of transcription factors involved in adrenal cortex formation, steroidogenesis and the hormonal response.
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