Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 38, Issue -, Pages 1088-1092Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0381088
Keywords
CID; Lcp5; neuroguidin; Rrp47; Rrp6; Sas10
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Funding
- Wellcome Trust [088306/Z/09/Z]
- Wellcome Trust [088306/Z/09/Z] Funding Source: Wellcome Trust
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The Sas10/C1D domain is found in a small group of eukaryotic proteins that have functions in RNA processing events, translational control and DNA repair mechanisms. The domain is predicted to be a-helical in nature and comprises approx. 80 amino acid residues. Whereas the Sas10/C1D domain has yet to be functionally characterized, available results suggest that this domain forms a binding surface for specific interactions with other proteins and can concomitantly interact with RNA or DNA. This property of the Sas10/C1D domain may facilitate this family of proteins to dock other proteins on to nucleic acid substrates.
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