Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 38, Issue -, Pages 1676-1680Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0381676
Keywords
crossing over; inversion; meiosis; recombination; synaptic adjustment; synaptonemal complex
Categories
Funding
- Russian Foundation for Basic Research [10 04 00008 a]
- Russian Ministry of Science and Education [02 740 11 0277]
- Russian Academy of Sciences
Ask authors/readers for more resources
Inversion heterozygotes are expected to suffer from reduced fertility and a high incidence of chromosomally unbalanced gametes due to recombination within the inverted region Non homologous synapsis of the inverted regions can prevent recombination there and diminish the deleterious effects of inversion heterozygosity The choice between non homologous and homologous synapsis depends on the size of inversion its genetic content its location in relation to the centromere and telomere and genetic background In addition there is a class of inversions in which homologous synapsis is gradually replaced by non homologous synapsis during meiotic progression This process is called synaptic adjustment The degree of synaptic adjustment depends critically on the presence and location of the COs (crossovers) within the inversion loop Only bivalents without COs within the loop and those with COs in the middle of the inversion can be completely adjusted and became linear
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available