4.8 Article

Cellular signalling:: Stressing the importance of PIP3

Journal

CURRENT BIOLOGY
Volume 11, Issue 9, Pages R371-R373

Publisher

CELL PRESS
DOI: 10.1016/S0960-9822(01)00197-X

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The lipid second messenger PIP3 was previously thought to be generated exclusively by type I PI 3-kinases. Now, a novel route of PIP3 synthesis, controlled by an unrelated enzyme family, has been discovered, increasing our understanding of the versatility of PIP3 in cellular signalling.

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