4.4 Article Proceedings Paper

Polyadenylation and degradation of mRNA in mammalian mitochondria: a missing link?

Journal

BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 36, Issue -, Pages 517-519

Publisher

PORTLAND PRESS LTD
DOI: 10.1042/BST0360517

Keywords

mitochondrion; mRNA stability; polyadenylation; polynucleotide phosphorylase (PNPase)

Funding

  1. Wellcome Trust [074454] Funding Source: Medline

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mRNA turnover in human mitochondria, one of the key mechanisms governing mitochondrial gene expression, still presents an unsolved puzzle. The present article summarizes the current research on the mechanisms and enzymes that may be involved in that process.

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