The efficacy of Xialine® in patients with xerostomia resulting from radiotherapy for head and neck cancer:: a pilot-study

Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.