Journal
MECHANISMS OF DEVELOPMENT
Volume 103, Issue 1-2, Pages 137-139Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0925-4773(01)00330-6
Keywords
mutants; flh(-/-); oep(-/-); yolk sac; early hepatic cells
Categories
Ask authors/readers for more resources
Formation of the liver in zebrafish has been analyzed during normal embryogenesis using ceruloplasmin (Cp) as a specific marker. The asymmetric expression of Cp has been detected in dorsal endoderm at 16 hpf and later in the early hepatic cells in the yolk sac. The liver primordium can be detected after 32 hpf. In oep(-/-) mutant, which lacks dorsal endoderm, the liver fails to form. In the notochordless flh(-/-) mutant, the asymmetry of the liver has been lost. Therefore the notochord, dorsal endoderm and endoderm of the yolk sac play a role in liver formation in zebrafish. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available