4.6 Article

Combination of Correctors Rescue ΔF508-CFTR by Reducing Its Association with Hsp40 and Hsp27

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Correcting the Cystic Fibrosis Disease Mutant, A455E CFTR

Liudmila Cebotaru et al.

PLOS ONE (2014)

Review Biochemistry & Molecular Biology

Molecular Chaperone Functions in Protein Folding and Proteostasis

Yujin E. Kim et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)

Article Pharmacology & Pharmacy

Rescuing Mutant CFTR: A Multi-task Approach to a Better Outcome in Treating Cystic Fibrosis

Margarida D. Amaral et al.

CURRENT PHARMACEUTICAL DESIGN (2013)

Article Biochemistry & Molecular Biology

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

Tsukasa Okiyoneda et al.

NATURE CHEMICAL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences

Juan L. Mendoza et al.

Review Critical Care Medicine

Managing Cystic Fibrosis Strategies That Increase Life Expectancy and Improve Quality of Life

Malena Cohen-Cymberknoh et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Cell Biology

Modeling general proteostasis: proteome balance in health and disease

Daniela M. Roth et al.

CURRENT OPINION IN CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

Fredrick Van Goor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

Emergent Properties of Proteostasis in Managing Cystic Fibrosis

William E. Balch et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Structure and Dynamics of NBD1 from CFTR Characterized Using Crystallography and Hydrogen/Deuterium Exchange Mass Spectrometry

H. A. Lewis et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Article Medicine, General & Internal

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation

Frank J. Accurso et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Multidisciplinary Sciences

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Fredrick Van Goor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Biochemistry & Molecular Biology

CFTR function and prospects for therapy

John R. Riordan

ANNUAL REVIEW OF BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and ΔF508 processing

Liudmila Cebotaru et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

Small heat-shock proteins select ΔF508-CFTR for endoplasmic reticulum-associated degradation

Annette Ahner et al.

MOLECULAR BIOLOGY OF THE CELL (2007)

Article Physiology

Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

F Van Goor et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)

Article Medicine, Research & Experimental

Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening

N Pedemonte et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Biochemistry & Molecular Biology

CFTR and chaperones - Processing and degradation

MD Amaral

JOURNAL OF MOLECULAR NEUROSCIENCE (2004)