Journal
JOURNAL OF NATURAL PRODUCTS
Volume 64, Issue 5, Pages 659-660Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np000604g
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Investigation of the whole plant of Isodon excisus resulted in the isolation of two new apoptosis inhibitors (1 and 2). Compounds 1 and 2 inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 10.2 and 52.4 mug/mL, respectively. The structures of 1 and 2 were determined by spectral data interpretation.
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