Journal
JOURNAL OF BACTERIOLOGY
Volume 183, Issue 10, Pages 3204-3210Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.183.10.3204-3210.2001
Keywords
-
Categories
Funding
- NIGMS NIH HHS [GM-30692, GM-32506/5120MZ, R37 GM032506, R01 GM032506] Funding Source: Medline
Ask authors/readers for more resources
During development of the symbiotic soil bacterium Sinorhizobium meliloti into nitrogen-fixing bacteroids, DNA replication and cell division cease and the cells undergo profound metabolic and morphological changes. Regulatory genes controlling the early stages of this process have not been identified, As a first step in the search for regulators of these events, we report the isolation and characterization of a ctrA gene from S. meliloti, We show that the S, meliloti CtrA belongs to the CtrA-like family of response regulators found in several cu-proteobacteria, In Caulobacter crescentus, CtrA is essential and Is a global regulator of multiple cell cycle functions, etr,l is also an essential gene in S, meliloti, and it is expressed similarly to the autoregulated C, crescentus ctrA in that both genes have complex promoter regions which bind phosphorylated CtrA.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available