Related references
Note: Only part of the references are listed.X marks the spot: Does it matter that O-GlcNAc Transferase is an X-linked gene?
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AUTOPHAGY (2013)
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Loss of Akt1 in Mice Increases Energy Expenditure and Protects against Diet-Induced Obesity
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O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases
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O-Linked-N-Acetylglucosamine Cycling and Insulin Signaling Are Required for the Glucose Stress Response in Caenorhabditis elegans
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GENETICS (2011)
A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome
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O-linked β-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
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Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis
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CHEMISTRY & BIOLOGY (2010)
Blocking O-Linked GlcNAc Cycling in Drosophila Insulin-producing Cells Perturbs Glucose-Insulin Homeostasis
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Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages
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Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity
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O-GlcNAc cycling: Emerging roles in development and epigenetics
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O-GIcNAc signaling: a metabolic link between diabetes and cancer?
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PHYSIOLOGICAL REVIEWS (2009)
Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression
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SCIENCE (2009)
Regulation of Akt signaling by O-GlcNAc in euglycemia
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Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance
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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
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NATURE (2008)
O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)
Distinctive inhibition of O-GlcNAcase isoforms by an α-GlcNAc thiolsulfonate
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Obesity-associated improvements in metabolic profile through expansion of adipose tissue
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JOURNAL OF CLINICAL INVESTIGATION (2007)
Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation
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Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats
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GLYCOBIOLOGY (2007)
Caenorhabditis elegans ortholog of a diabetes susceptibility locus:: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Enzymatic characterization of O-GlcNAcase isoforms using a fluorogenic GlcNAc substrate
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CARBOHYDRATE RESEARCH (2006)
An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid
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A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-β-D glucosaminidase is associated with type 2 diabetes in Mexican Americans
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DIABETES (2005)
Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance
M Hazel et al.
ENDOCRINOLOGY (2004)
Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability
N O'Donnell et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
O-GlcNAc a sensor of cellular state:: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
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BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2004)
Dynamic interplay between O-GlcNAc and O-phosphate: the sweet side of protein regulation
C Slawson et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2003)
GSK-3: tricks of the trade for a multi-tasking kinase
BW Doble et al.
JOURNAL OF CELL SCIENCE (2003)
Insulin resistance of glycogen synthase mediated by O-linked N-acetylglucosamine
GJ Parker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene
JA Hanover et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Prediction of structure and functional residues for O-GlcNAcase, a divergent homologue of acetyltransferases
J Schultz et al.
FEBS LETTERS (2002)
Analysis of MGEA5 on 10q24.1-q24.3 encoding the β-O-linked N-acetylglucosaminidase as a candidate gene for type 2 diabetes mellitus in Pima Indians
VS Farook et al.
MOLECULAR GENETICS AND METABOLISM (2002)
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
DA McClain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes
K Vosseller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Hexosamines as mediators of nutrient sensing and regulation in diabetes
DA McClain
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2002)
Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice
KU Wagner et al.
TRANSGENIC RESEARCH (2001)
Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology
C Babinet et al.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2001)
Glycan-dependent signaling: O-linked N-acetylglucosamine
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FASEB JOURNAL (2001)
Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a β-N-acetylglucosaminidase
N Comtesse et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Dynamic O-glycosylation of nuclear and cytosolic proteins -: Cloning and characterization of a neutral, cytosolic β-N-acetylglucosaminidase from human brain
Y Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The expression of adipogenic genes is decreased in obesity and diabetes mellitus
ST Nadler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Hexosamines stimulate leptin production in transgenic mice
DA McClain et al.
ENDOCRINOLOGY (2000)
Inhibition of glycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes
SJ Oreña et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
R Shafi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)