Journal
BIOCHEMICAL PHARMACOLOGY
Volume 75, Issue 1, Pages 63-75Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bcp.2007.06.043
Keywords
addiction; impulse control disorders; pathological gambling; brain imaging; genetics
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Funding
- NIDA NIH HHS [R01-DA020908, R01 DA019039-03, R01 DA019039, R01 DA020908-03, R01 DA020908, R01-DA019039] Funding Source: Medline
- NIMH NIH HHS [T32-MH19961, T32 MH019961] Funding Source: Medline
- NATIONAL INSTITUTE OF MENTAL HEALTH [T32MH019961] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA019039, R01DA020908] Funding Source: NIH RePORTER
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Impulse control disorders (ICDs), including pathological gambling, trichotillomania, kleptomania and others, have been conceptualized to lie along an impulsive-compulsive spectrum. Recent data have suggested that these disorders may be considered addictions. Here, we review the genetic and neuropathological bases of the impulse control disorders and consider the disorders within these non-mutually exclusive frameworks. (C) 2007 Elsevier Inc. All rights reserved.
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