Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 75, Issue 2-3, Pages 191-195Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0378-8741(01)00186-6
Keywords
Trigonella foenum-graecum; hypoglycaemic activity
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Trigonella foenum-graecum (Fenugreek) (Leguminosae) is employed as a herbal medicine. Its seeds are known for their carminative, tonic and antidiabetic effects. A curative dose of Trigonella foenum-graecum also produces antiulcer action. In this study we have investigated the hypoglycaemic activities of the aqueous extract of the seeds Trigonella foenum-graecum in normal mice using oral route of adminstration. The methanolic extract administered through the same route produced hypoglycaemic effect only at the dose of 1 g/kg body weight. The aqueous extract is under further investigation to determine the chemical structure of the active component. The presence of hypoglycaemic activity in aqueous and methanolic extract indicates that the active compounds are polar in nature. (C) 2001 published by Elsevier Science Ireland Ltd.
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