Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 11, Issue 9, Pages 1193-1196Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(01)00190-1
Keywords
-
Categories
Funding
- NCI NIH HHS [CA-17625] Funding Source: Medline
- NIAID NIH HHS [AI-33066] Funding Source: Medline
Ask authors/readers for more resources
A series of 2 ' ,3 ' ,4 ' ,6,7-substituted 2-aryl quinazolinones were synthesized and evaluated for biological activity. Among them, 17 displayed significant growth inhibitory action against a panel of tumor cell lines. Compound 17 was also a potent inhibitor of tubulin polymerization. Compounds 8-10 displayed selective activity against P-gp-expressing epidermoid carcinoma of the nasopharynx. (C) 2001 Elsevier Science Ltd. all rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
