4.8 Article

Monitoring solid-phase glycoside synthesis with 19F NMR spectroscopy

Journal

ORGANIC LETTERS
Volume 3, Issue 10, Pages 1463-1466

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol015759+

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[GRAPHICS] A simple and efficient method for monitoring and optimizing carbohydrate synthesis on polymeric support by using F-19 NMR spectroscopy is described. The method relies on the use of fluorinated variants of protective groups that are in common use in oligosaccharide synthesis.

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