Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 11, Issue 3, Pages 287-292Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(00)00192-1
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Although the underlying mechanisms of ageing are not understood, it is known that the longevity of the nematode Caenorhabditis elegans is modulated by an insulin/IGF-signalling pathway. The focus now is on how this pathway is regulated, how it controls nematode ageing, and how this relates to the ageing process in higher animals.
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