Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 13, Issue 3, Pages 326-331Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(00)00222-3
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Funding
- NCI NIH HHS [CA89189, R01 CA89294] Funding Source: Medline
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The function of leukocytes is regulated by the integration of positive and negative signals received through cell surface receptors. Related receptors with similar extracellular domains and often binding the same ligands can transmit either inhibitory or activating signals. Studies are beginning to reveal how these 'paired receptors' control immune functions.
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