4.7 Article

Chemoprotective effect of Ixora coccinea L. flowers on cisplatin induced toxicity in mice

Journal

PHYTOTHERAPY RESEARCH
Volume 15, Issue 4, Pages 364-366

Publisher

JOHN WILEY & SONS LTD
DOI: 10.1002/ptr.727

Keywords

Ixora coccinea; cisplatin; chemoprotection; ursolic acid; anti-lipid peroxidative effects

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The active fraction from Ixora coccinea flowers prevented a decrease in body weight, haemoglobin levels and leucocyte counts of mice treated with cisplatin, It also significantly prolonged the life span of cisplatin treated mice and maintained their blood urea nitrogen levels in the near normal range, indicating its chemoprotective effects. Copyright (C) 2001 John Wiley & Sons, Ltd.

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