Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 13, Issue 3, Pages 317-325Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(00)00221-1
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The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-gamma and downstream pathways.
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