4.4 Article

β-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2)

Journal

JOURNAL OF BACTERIOLOGY
Volume 183, Issue 11, Pages 3526-3530

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.183.11.3526-3530.2001

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The Streptomyces coelicolor fab (fatty acid biosynthesis) gene cluster (fabD-fabH-acpP-fabF) is cotranscribed to produce a leaderless mRNA transcript. One of these genes, fabH, encodes a ketoacyl synthase III that is essential to and is proposed to be responsible for initiation of fatty acid biosynthesis in S. coelicolor.

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