Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 49, Issue 6, Pages 773-775Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.49.773
Keywords
Sinopodophyllum emodi; Berberidaceae; lignan; isopodophyllotoxin 7 '-O-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside; 4-demethyl-picropodophyllotoxin 7 '-O-beta-D-glucopyranoside
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Two new aryltetralin-type lignans, isopodophyllotoxin 7 ' -O-beta -D-glucopyranosyl-(1 -->6)-beta -D-glucopyranoside (1) and 4-demethyl-picropodophyllotoxin 7 ' -O-beta -D-glucopyranoside (2), along with eight known podophyllotoxin derivatives: 4-demethyl-podophyllotoxin 7 ' -O-beta -D-glucopyranoside (3), podophyllotoxin 7 ' -O-beta -D-glucopyranoside (4), deoxypodophyllotoxin (5), picropodophyllotoxin (6), podophyllotoxin (7). 4-demethyl-picropodophyllotoxin (8), 4-demethyl-podophyllotoxin (9), and 4-demethyl-deoxypodophyllotoxin (10), were isolated from the roots and rhizomes of Sinopodophyllum emodi (WALL.) YING (Berberidaceae). Their structures were identified based on NMR spectral data and chemical evidence.
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