4.4 Article

Convenient and stereoselective synthesis of (Z)-1-bromo-1-alkenes by microwave-induced reaction

Journal

TETRAHEDRON LETTERS
Volume 42, Issue 23, Pages 3893-3896

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(01)00595-0

Keywords

(Z)-vinyl bromide; alpha,beta-unsaturated carboxylic acids decarboxylation; microwave irradiation

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(Z)-l-Bromo-l-alkenes were stereoselectively prepared in high yields in a short reaction time (0.2 1.0 min) by microwave irradiation of the corresponding 2,3-dibromoalkanoic acids in DMF in the presence of triethylamine. (C) 2001 Elsevier Science Ltd. All rights reserved.

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