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Benzannulation reactions of Fischer carbene complexes for the synthesis of indolocarbazoles

Journal

TETRAHEDRON
Volume 57, Issue 24, Pages 5199-5212

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(01)00360-X

Keywords

benzannulation; carbene complex; indolocarbazoles; palladium catalyzed cross-coupling

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The synthesis of indolocarbazoles was achieved via photochemical and thermal annulation reactions of chromium Fischer carbene complexes. This methodology allows for facile incorporation of hydrogen bonding functionality which complements the pharmacophore contained within bioactive indolocarbazole natural products. (C) 2001 Elsevier Science Ltd. All rights reserved.

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