Journal
OPTICS LETTERS
Volume 26, Issue 12, Pages 893-895Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.26.000893
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We present a normalized Born expansion that facilitates fluorescence reconstructions in turbid, tissue-like media. The algorithm can be particularly useful for tissue investigations of fluorochrome distribution in vivo, since it does not require absolute photon-field measurements or measurements before contrast-agent administration. This unique advantage can be achieved only in fluorescence mode. We used this algorithm to three-dimensionally image and quantify an indocyanine fluorochrome phantom, using a navel fluorescence tomographic imager developed for animals. (C) 2001 Optical Society of America.
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