Journal
ORGANIC LETTERS
Volume 3, Issue 13, Pages 2077-2079Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0160396
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Funding
- NCI NIH HHS [T32CA09112] Funding Source: Medline
- NIGMS NIH HHS [GM46059] Funding Source: Medline
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[GRAPHICS] A general catalytic coupling of arylboronic acids and amines is reported. This room-temperature coupling was realized through the use of catalytic copper(II) acetate, 2,6-lutidine as base, and myristic acid as an additive. Functionalized aniline substrates provided the diarylamine coupling products in good yield (58-91%), A variety of alkylamines were also successfully coupled to give N-alkyl anilines in moderate yield (50-64%).
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