Immunotherapy historical perspective

Objective: To review early history of specific immunotherapy, particularly the contribution of Robert A. Cooke. Data Sources: Review of literature. Conclusions: Cooke was an important investigator developing the basic method of immunotherapy as it is practiced today. His contributions to the field of allergy are staggering. They include the elucidation of blocking antibodies, passive transfers, dosage techniques, testing techniques, and more. It is our hope this consensus conference will lead to more national and international collaborative efforts focusing on different subtopics of allergen immunotherapy. We intend to bring cutting edge information, discussions, and consensus agreements for our own members, for other physicians, and for the public at large.