Journal
JOURNAL OF VIROLOGY
Volume 75, Issue 14, Pages 6687-6691Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.75.14.6687-6691.2001
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Cynomolgus macaques (Macaca fascicularis) infected with influenza virus A/Hong Kong/156/97 (H5N1) developed acute respiratory distress syndrome and fever associated with a necrotizing interstitial pneumonia. Reverse transcription PCR, virus isolation, and immunohistochemistry showed that the respiratory tract is the major target of the virus.
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