Journal
INTERNAL MEDICINE
Volume 40, Issue 7, Pages 654-657Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.40.654
Keywords
acute lymphoblastic leukemia; irinotecan (CPT-11); diarrhea; bacteremia; liver abscesses
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Multiple brain and liver abscesses developed immediately after Bacillus cereus bacteremia in a neutropenic patient with acute lymphoblastic leukemia. After even 8 weeks of antimicrobial chemotherapy together with administration of granulocyte colony-stimulating factor, every infectious process disappeared but the patient's headache has still persisted. Because the wall of one brain abscess became thin and was in danger of rupturing into the ventricle, surgical drainage was performed, resulting in disappearance of headache and resolution of brain abscess. The present case indicates that a combined medical and surgical approach is mandatory to treat patients with brain abscesses.
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