4.6 Article

Di-2-pyridylketone 4,4-Dimethyl-3-thiosemicarbazone (Dp44mT) Overcomes Multidrug Resistance by a Novel Mechanism Involving the Hijacking of Lysosomal P-Glycoprotein (Pgp)

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

Young Hee Choi et al.

CURRENT PHARMACEUTICAL DESIGN (2014)

Article Biochemistry & Molecular Biology

P-glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration

Tetsuo Yamagishi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Pharmacology & Pharmacy

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

Y. Yu et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Article Medicine, Research & Experimental

N-myc downstream regulated gene 1 modulates Wnt-ß-catenin signalling and pleiotropically suppresses metastasis

Wen Liu et al.

EMBO MOLECULAR MEDICINE (2012)

Review Chemistry, Medicinal

The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review

Naseem Akhtar et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2011)

Article Neurosciences

Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism

Sowmya V. Yelamanchili et al.

MOLECULAR NEURODEGENERATION (2011)

Article Pharmacology & Pharmacy

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

J. C. McGrath et al.

BRITISH JOURNAL OF PHARMACOLOGY (2010)

Article Biochemistry & Molecular Biology

Correlation of concentrations of selected trace elements with Gleason grade of prostate tissues

A. Banas et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2010)

Article Chemistry, Medicinal

Triggering Liposomal Drug Release With a Lysosomotropic Agent

Subin Xiong et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Biochemistry & Molecular Biology

Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line

L. Murphy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2008)

Review Pharmacology & Pharmacy

ABC multidrug transporters: structure, function and role in chemoresistance

Frances J. Sharom

PHARMACOGENOMICS (2008)

Article Biochemistry & Molecular Biology

Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

Peter V. E. Van den Berghe et al.

BIOCHEMICAL JOURNAL (2007)

Article Chemistry, Multidisciplinary

Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar

Sebastien Bihorel et al.

PHARMACEUTICAL RESEARCH (2007)

Review Multidisciplinary Sciences

Multiple molecular mechanisms for multidrug resistance transporters

Christopher F. Higgins

NATURE (2007)

Review Microscopy

A guided tour into subcellular colocalization analysis in light microscopy

S. Bolte et al.

JOURNAL OF MICROSCOPY (2006)

Article Multidisciplinary Sciences

A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

Megan Whitnall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multildrug resistance-associated protein 1

Ralph N. Watts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Pharmacology & Pharmacy

What kinds of substrates show p-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine

Takuo Ogihara et al.

DRUG METABOLISM AND PHARMACOKINETICS (2006)

Article Engineering, Environmental

Kinetics and mechanisms of DMSO (dimethylsulfoxide) degradation by UV/H2O2 process

Y Lee et al.

WATER RESEARCH (2004)

Review Pharmacology & Pharmacy

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

AH Schinkel et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)

Article Biochemistry & Molecular Biology

The radioprotective agent, amifostine, suppresses the reactivity of intralysosomal iron

ZQ Yu et al.

REDOX REPORT (2003)

Review Oncology

The role of ABC transporters in clinical practice

GD Leonard et al.

ONCOLOGIST (2003)

Review Biochemistry & Molecular Biology

The hallmarks of cancer

D Hanahan et al.