Related references
Note: Only part of the references are listed.Phylogenetic conservation of protein-lipid motifs in pentameric ligand-gated ion channels
Francisco J. Barrantes
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Nicotinic acetylcholine receptor-lipid interactions: Mechanistic insight and biological function
John E. Baenziger et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold
Giovanni Gonzalez-Gutierrez et al.
JOURNAL OF GENERAL PHYSIOLOGY (2015)
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
Stuart A. Forman et al.
NEUROPHARMACOLOGY (2015)
The role of the M4 lipid-sensor in the folding, trafficking, and allosteric modulation of nicotinic acetylcholine receptors
Camille M. Henault et al.
NEUROPHARMACOLOGY (2015)
Conformational Changes Underlying Desensitization of the Pentameric Ligand-Gated Ion Channel ELIC
Monica N. Kinde et al.
STRUCTURE (2015)
Role of the Fourth Transmembrane α Helix in the Allosteric Modulation of Pentameric Ligand-Gated Ion Channels
Casey L. Carswell et al.
STRUCTURE (2015)
Intramembrane Aromatic Interactions Influence the Lipid Sensitivities of Pentameric Ligand-gated Ion Channels
Casey L. Carswell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Structural Requirements in the Transmembrane Domain of GLIC Revealed by Incorporation of Noncanonical Histidine Analogs
Matthew Rienzo et al.
CHEMISTRY & BIOLOGY (2014)
Structural Basis for Allosteric Coupling at the Membrane-Protein Interface in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC)
Phanindra Velisetty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
ELIC- α 7 Nicotinic Acetylcholine Receptor ( α 7nAChR) Chimeras Reveal a Prominent Role of the ExtracellularTransmembrane Domain Interface in Allosteric Modulation
Tommy S. Tillman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
Ludovic Sauguet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
Ludovic Sauguet et al.
EMBO JOURNAL (2013)
Structural Sensitivity of a Prokaryotic Pentameric Ligand-gated Ion Channel to Its Membrane Environment
Jonathan M. Labriola et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors
Corrie J. B. daCosta et al.
NATURE CHEMICAL BIOLOGY (2013)
Gating of Pentameric Ligand-Gated Ion Channels: Structural Insights and Ambiguities
Corrie J. B. daCosta et al.
STRUCTURE (2013)
Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions
Cosma D. Dellisanti et al.
PLOS BIOLOGY (2013)
Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor
Daniel Caballero-Rivera et al.
CHANNELS (2012)
Intramembrane Proton Binding Site Linked to Activation of Bacterial Pentameric Ion Channel
Hai-Long Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Desensitization Mechanism in Prokaryotic Ligand-gated Ion Channel
Phanindra Velisetty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Conformational Transitions Underlying Pore Opening and Desensitization in Membrane-embedded Gloeobacter violaceus Ligand-gated Ion Channel (GLIC)
Phanindra Velisetty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A locally closed conformation of a bacterial pentameric proton-gated ion channel
Marie S. Prevost et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals
Giovanni Gonzalez-Gutierrez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
Jianjun Pan et al.
NATURE COMMUNICATIONS (2012)
Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations
Iwan Zimmermann et al.
PLOS BIOLOGY (2012)
X-ray structures of general anesthetics bound to their molecular targets
Hugues Nury et al.
M S-MEDECINE SCIENCES (2011)
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Hugues Nury et al.
NATURE (2011)
3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels
John E. Baenziger et al.
NEUROPHARMACOLOGY (2011)
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family
Guillaume Duret et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC
Iwan Zimmermann et al.
PLOS BIOLOGY (2011)
An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors
Svenja Haeger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
A Lipid-dependent Uncoupled Conformation of the Acetylcholine Receptor
Corrie J. B. daCosta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Anionic Lipids Allosterically Modulate Multiple Nicotinic Acetylcholine Receptor Conformational Equilibria
Corrie J. B. daCosta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE (2009)
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
Nicolas Bocquet et al.
NATURE (2009)
Importance of the C-terminus of the human 5-HT3A receptor subunit
Amy S. Butler et al.
NEUROPHARMACOLOGY (2009)
Tryptophan scanning of the acetylcholine receptor's βM4 transmembrane domain Decoding allosteric linkage at the lipid-protein interface with ion-channel gating
Rosedelma Diaz-De Leon et al.
CHANNELS (2008)
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE (2008)
Lipid composition alters drug action at the nicotinic acetylcholine receptor
John E. Baenziger et al.
MOLECULAR PHARMACOLOGY (2008)
Acetylcholine receptor gating at extracellular transmembrane domain interface: the Cys-loop and M2-M3 linker
Archana Jha et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
Nicolas Bocquet et al.
NATURE (2007)
Slow-channel mutation in acetylcholine receptor αM4 domain and its efficient knockdown
Xin-Ming Shen et al.
ANNALS OF NEUROLOGY (2006)
Assessing the lipid requirements of the Torpedo californica nicotinic acetylcholine receptor
AK Hamouda et al.
BIOCHEMISTRY (2006)
Molecular tuning of fast gating in pentameric ligand-gated ion channels
T Grutter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
WY Lee et al.
NATURE (2005)
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
SCR Lummis et al.
NATURE (2005)
Structural and dynamic studies of the γ-M4 trans-membrane domain of the nicotinic acetylcholine receptor
PTF Williamson et al.
MOLECULAR MEMBRANE BIOLOGY (2005)
Fluorescence and molecular dynamics studies of the acetylcholine receptor γM4 transmembrane peptide in reconstituted systems
SS Antollini et al.
MOLECULAR MEMBRANE BIOLOGY (2005)
Conformational dynamics of the nicotinic acetylcholine receptor channel: A 35-ns molecular dynamics simulation study
YC Xu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric α7-5HT3A receptor
S Pons et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Tryptophan scanning mutagenesis of the γM4 transmembrane domain of the acetylcholine receptor from Torpedo californica
A Ortiz-Acevedo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural dynamics of the M4 transmembrane segment during acetylcholine receptor gating
A Mitra et al.
STRUCTURE (2004)
Mutations in congenital myasthenic syndromes reveal an ε subunit C-terminal cysteine, C470, crucial for maturation and surface expression of adult AChR
J Ealing et al.
HUMAN MOLECULAR GENETICS (2002)
A transmembrane motif governs the surface trafficking of nicotinic acetylcholine receptors
JM Wang et al.
NATURE NEUROSCIENCE (2002)
Subunit-selective contribution to channel Gating of the M4 domain of the nicotinic receptor
C Bouzat et al.
BIOPHYSICAL JOURNAL (2002)
Lipid-protein interactions at the nicotinic acetylcholine receptor - A functional coupling between nicotinic receptors and phosphatidic acid-containing lipid bilayers
CJB daCosta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Functional effects of periodic tryptophan substitutions in the α M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor
S Tamamizu et al.
BIOCHEMISTRY (2000)
Nicotinic receptor fourth transmembrane domain - Hydrogen bonding by conserved threonine contributes to channel gating kinetics
C Bouzat et al.
JOURNAL OF GENERAL PHYSIOLOGY (2000)
Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor
JE Baenziger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
