Journal
JOURNAL OF APPLIED PHYSICS
Volume 90, Issue 1, Pages 421-426Publisher
AMER INST PHYSICS
DOI: 10.1063/1.1376412
Keywords
-
Categories
Ask authors/readers for more resources
A longitudinal hemispherical standing-wave ultrasonic trap for size-selective separation of microspheres in small-diameter capillaries is described. The trap utilizes the competition between acoustic radiation forces and viscous drag forces on spheres suspended in a liquid inside 20-75-mum-diam fused silica capillaries. Experiments performed on 3.0- and 4.7-mum-diam latex spheres demonstrate the principles of trapping and verify the theoretically calculated size-dependent forces on the spheres. The spheres are detected by the use of laser-induced fluorescence. The goal is to use the trap for separation and ultrahigh-sensitivity detection of trace amounts of proteins and other macromolecules containing two antigenic sites, by binding the target molecule with high specificity to antibody-coated latex spheres. (C) 2001 American Institute of Physics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available