Journal
BRAIN RESEARCH
Volume 906, Issue 1-2, Pages 190-197Publisher
ELSEVIER
DOI: 10.1016/S0006-8993(01)02581-1
Keywords
ventral tegmental area; GABA; reinforcement; discharge activity; intracranial self-stimulation; medial forebrain bundle
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Funding
- NIAAA NIH HHS [R01 AA013666] Funding Source: Medline
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Dopamine neurons in the ventral tegmental area (VTA) have been implicated in rewarded behaviors, including intracranial self-stimulation (ICSS). We demonstrate, in unrestrained rats, that the discharge activity of a homogeneous population of presumed VTA GABA neurons, implicated in cortical arousal. increases before ICSS of the medial forebrain bundle (MFB). These findings suggest that VTA GABA neurons may be involved in the attentive processes related to brain stimulation reward (BSR). (C) 2001 Published by Elsevier Science B.V.
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