4.5 Article

A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 11, Issue 13, Pages 1769-1773

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(01)00300-6

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Funding

  1. NIGMS NIH HHS [GM 52324] Funding Source: Medline

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We have prepared several mechanism-based affinity-labeling agents for possible use in isolating N-acetylglucosaminidase, in which an N-acetylglucosamine is linked to an o-monofluoro- or difluoro-methyl phenoxy glycoside with or without a cleavable disulfide group in the tether to biotin. (C) 2001 Elsevier Science Ltd. All rights reserved.

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