Journal
TETRAHEDRON LETTERS
Volume 42, Issue 31, Pages 5203-5205Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(01)00978-9
Keywords
Meldrum's acid; water; uncatalysed reaction; Knoevenagel condensation; arylidene Meldrum's acid; environmentally benign synthesis
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The environment-friendly condensation of Meldrum's acid and aromatic, heteroaromatic and hindered aliphatic aldehydes is performed carrying out the reaction in water at 75 degreesC for 2 h, avoiding the addition of any catalyst. (C) 2001 Elsevier Science Ltd. All rights reserved.
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