Related references
Note: Only part of the references are listed.Dual-Specificity Phosphatases as Molecular Targets for Inhibition in Human Disease
Pablo Rios et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
Yun Sok Lee et al.
CELL (2014)
Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
Shinya U. Amano et al.
CELL METABOLISM (2014)
Macrophage HIF-2α Ameliorates Adipose Tissue Inflammation and Insulin Resistance in Obesity
Sung Sik Choe et al.
DIABETES (2014)
Local proliferation of macrophages in adipose tissue during obesity-induced inflammation
Julia Haase et al.
DIABETOLOGIA (2014)
Macrophages, Immunity, and Metabolic Disease
Joanne C. McNelis et al.
IMMUNITY (2014)
IL-4 reduces the proangiogenic capacity of macrophages by down-regulating HIF-1α translation
Nathalie Dehne et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2014)
N-Acetylcysteine Attenuates Ischemia-Reperfusion-Induced Apoptosis and Autophagy in Mouse Liver via Regulation of the ROS/JNK/Bcl-2 Pathway
Chengfen Wang et al.
PLOS ONE (2014)
Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice
S. Fujisaka et al.
DIABETOLOGIA (2013)
Immune Regulation in Obesity-Associated Adipose Inflammation
Jonathan M. Han et al.
JOURNAL OF IMMUNOLOGY (2013)
Inflammasome-Mediated Secretion of IL-1β in Human Monocytes through TLR2 Activation; Modulation by Dietary Fatty Acids
Ryan G. Snodgrass et al.
JOURNAL OF IMMUNOLOGY (2013)
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
G. M. Tannahill et al.
NATURE (2013)
HYPOXIA AND ADIPOSE TISSUE FUNCTION AND DYSFUNCTION IN OBESITY
Paul Trayhurn
PHYSIOLOGICAL REVIEWS (2013)
Mitogen-activated protein kinases in innate immunity
J. Simon C. Arthur et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways
Shurong Huang et al.
JOURNAL OF LIPID RESEARCH (2012)
The cellular and signaling networks linking the immune system and metabolism in disease
Olivia Osborn et al.
NATURE MEDICINE (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
The adipocyte as an endocrine organ in the regulation of metabolic homeostasis
H. James Harwood
NEUROPHARMACOLOGY (2012)
Adipose Tissue Vascularization: Its Role in Chronic Inflammation
Jianping Ye
CURRENT DIABETES REPORTS (2011)
Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states
David L. Morris et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2011)
Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells
R. W. O'Rourke et al.
DIABETOLOGIA (2011)
Signaling by the Phosphatase MKP-1 in Dendritic Cells Imprints Distinct Effector and Regulatory T Cell Fates
Gonghua Huang et al.
IMMUNITY (2011)
Adipose tissue remodeling and obesity
Kai Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Unsaturated FAs prevent palmitate-induced LOX-1 induction via inhibition of ER stress in macrophages
Junichi Ishiyama et al.
JOURNAL OF LIPID RESEARCH (2011)
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
Haitao Wen et al.
NATURE IMMUNOLOGY (2011)
Macrophage-mediated inflammation in metabolic disease
Ajay Chawla et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Acute Oxidative Stress Can Reverse Insulin Resistance by Inactivation of Cytoplasmic JNK
Alina Berdichevsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages
Liliana Haversen et al.
ATHEROSCLEROSIS (2009)
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
Hsin-Yu Fang et al.
BLOOD (2009)
Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
Magdalena Pasarica et al.
DIABETES (2009)
HIF-1 in the inflammatory microenvironment
Nathalie Dehne et al.
EXPERIMENTAL CELL RESEARCH (2009)
Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
Jin Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells
David W. Chan et al.
CARCINOGENESIS (2008)
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Jordi Rius et al.
NATURE (2008)
DUSP meet immunology: Dual specificity MAPK phosphatases in control of the inflammatory response
Roland Lang et al.
JOURNAL OF IMMUNOLOGY (2006)
Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity
Eoin P. Cummins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses
HB Chi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes
GS Hotamisligil
DIABETES (2005)
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation
KD Mansfield et al.
CELL METABOLISM (2005)
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
RD Guzy et al.
CELL METABOLISM (2005)
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
JK Brunelle et al.
CELL METABOLISM (2005)
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
H Kamata et al.
CELL (2005)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Effects of N-acetylcysteine in hepatic ischemia-reperfusion injury during hemorrhagic shock
AOV Portella et al.
TRANSPLANTATION PROCEEDINGS (2004)
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
C Koumenis et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia -: A mechanism of O2 sensing
NS Chandel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)