Journal
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
Volume 23, Issue 2, Pages 233-255Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.berh.2009.03.004
Keywords
muscle biopsy; peripheral nerve biopsy; renal biopsy; salivary gland biopsy; skin biopsy; skin-muscle-fascia biopsy; subcutaneous fat biopsy; temporal artery biopsy
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Rheumatic and, in particular, connective tissue diseases involve many organ systems in addition to the joints. These include the skin and underlying tissues, muscles, salivary glands, nerves, kidneys and blood vessels. Biopsy specimens of these tissues can be helpful in establishing a diagnosis, assessing the extent and severity of organ involvement and monitoring therapy. This article describes the practical information on a clinical diagnosis that might indicate a need for biopsy. It outlines how to prepare the patient, how to perform the biopsy, what results are to be expected and which sequelae are possible. (C) 2009 Elsevier Ltd. All rights reserved.
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