Journal
CLINICAL IMMUNOLOGY
Volume 100, Issue 2, Pages 134-143Publisher
ACADEMIC PRESS INC
DOI: 10.1006/clim.2001.5075
Keywords
-
Categories
Funding
- NIAID NIH HHS [AI42669] Funding Source: Medline
- NIDDK NIH HHS [DK49106, DK32520, DK25306, DK36024, DK53006] Funding Source: Medline
Ask authors/readers for more resources
Type 1 diabetes in humans is a serious autoimmune disorder of children that is still poorly understood unpreventable, and irreversible. Study of its animal models, notably the NOD mouse and BB rat, has generated a wealth of information concerning genetics and immunopathogenesis, but that information has still not altered the way in which we treat children with diabetes. In this review we attempt to identify the most promising avenues of continuing research in these models and the most important issues that must be faced by the designers of human therapies based on the animal dataset. (C) 2001 Academic Press.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available