Journal
ANALYST
Volume 140, Issue 16, Pages 5444-5449Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5an00691k
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Funding
- Macquarie University Research Excellence Scheme postgraduate scholarship
- Northern Translational Cancer Research Unit (Kolling Institute of the University of Sydney) through a Cancer Institute NSW competitive grant
- Australian Research Council [DP110104958]
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In the search for N-glycan disease biomarkers current glycoanalytical methods may not be revealing a complete picture of precious samples, and we may be missing valuable structural information that fall outside analysis windows. We report a targeted strategy combining PGC-LC-ESI-MS with exoglycosidases to improve the relative quantitation of tri and tetra-antennary glycan classes.
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