Journal
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
Volume 24, Issue 8, Pages 1293-1294Publisher
FUTURA PUBL CO
DOI: 10.1046/j.1460-9592.2001.01293.x
Keywords
ventricular fibrillation; isoproterenol; Brugada syndrome
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Intravenous administration of isoproterenol restored the ST-segment configuration to nearly normal in the right precordial leads and completely prevented spontaneous VF attacks in a patient with Brugada syndrome. The formation of a Brugada-type ECG has been attributed to the transmural dispersion of repolarization of the right ventricular epicardium and related to modulation of the autonomic nervous system. Our case may provide clues to the pathophysiological mechanism of this syndrome.
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