Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 14, Issue -, Pages 2348-2353Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.14.210
Keywords
additive-free; catalyst-free; cycloaddition; enaminones; on water; 1,2,3-triazole
Categories
Funding
- National Natural Science Foundation of China [21562025]
- Natural Science Foundation of Jiangxi Province [20161ACB21010]
- Open Project of the Key Laboratory of Rheumatic Diseases of Traditional Chinese Medicine in Zhejiang Province
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The synthesis of 4-acyl-NH-1,2,3-triazoles has been accomplished with high efficiency through the cycloaddition reactions between N,N-dimethylenaminones and tosyl azide. This method is featured with extraordinary sustainability by employing water as the sole medium, free of any catalyst or additive, authentically mild conditions (40 degrees C stirring) as well as practical scalability.
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