4.5 Article

Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide

Journal

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 14, Issue -, Pages 2348-2353

Publisher

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.14.210

Keywords

additive-free; catalyst-free; cycloaddition; enaminones; on water; 1,2,3-triazole

Funding

  1. National Natural Science Foundation of China [21562025]
  2. Natural Science Foundation of Jiangxi Province [20161ACB21010]
  3. Open Project of the Key Laboratory of Rheumatic Diseases of Traditional Chinese Medicine in Zhejiang Province

Ask authors/readers for more resources

The synthesis of 4-acyl-NH-1,2,3-triazoles has been accomplished with high efficiency through the cycloaddition reactions between N,N-dimethylenaminones and tosyl azide. This method is featured with extraordinary sustainability by employing water as the sole medium, free of any catalyst or additive, authentically mild conditions (40 degrees C stirring) as well as practical scalability.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available