Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 10, Issue -, Pages 1706-1732Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.10.179
Keywords
multicomponent reaction; nucleoside analog; nucleoside antibiotics; nucleoside construction; nucleoside modification
Categories
Funding
- Warsaw University of Technology
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This review covers sixty original publications dealing with the application of multicomponent reactions (MCRs) in the synthesis of novel nucleoside analogs. The reported approaches were employed for modifications of the parent nucleoside core or for de novo construction of a nucleoside scaffold from non-nucleoside substrates. The cited references are grouped according to the usually recognized types of the MCRs. Biochemical properties of the novel nucleoside analogs are also presented (if provided by the authors).
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