Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 10, Issue -, Pages 641-652Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.10.56
Keywords
automation; flow chemistry; hydration; hydrogenation; sustainable processing
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Funding
- Pfizer Worldwide Research and Development
- Ralph Raphael studentship
- BP endowment
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Here we describe the use of a new open-source software package and a Raspberry Pi (R) computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide - a component of Rifater (R), used in the treatment of tuberculosis - and its reduced derivative piperazine-2-carboxamide.
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